Service Items
01
/Chiral Chemistry
The Chiral Homogeneity of Life: The fundamental "building blocks" of life—natural amino acids—are almost exclusively in the L-configuration, while sugars (such as ribose and glucose) are predominantly in the D-configuration. Biological macromolecules like proteins, DNA, and enzymes themselves possess highly chiral three-dimensional structures, acting like a lock that only accepts a specifically "handed" key.
The "Chiral Destiny" of Drugs:
Differences in Efficacy: When enantiomers interact with chiral biological targets (such as enzymes or receptors), they can produce completely different physiological effects.
Typically, only one enantiomer (the eutomer) possesses the desired therapeutic activity, while the other may be inactive, have low activity, or even be toxic.
Our Service Focus
Utilizing chemical process technologies, such as metal catalysis and enzymatic catalysis, to efficiently synthesize chiral pharmaceutical compounds.
02
/Coupling Chemistry
Coupling chemistry : generally refers to a class of chemical reactions that connect two molecular fragments to build more complex molecules by forming carbon-carbon or carbon-heteroatom bonds.
Its core characteristics include:
- Bond Formation: Focuses on creating new covalent bonds between two pre-made, functionalized fragments.
- High Selectivity: Achieves high site selectivity and functional group compatibility, even within complex molecules.
- Modular Synthesis: Allows for the rapid assembly of target molecule libraries from diverse "building blocks."
Our Service Focus:
Suzuki-Miyaura Coupling: The palladium-catalyzed cross-coupling of organoboron reagents with organic halides. It is the most widely applied coupling reaction, known for its mild conditions and excellent functional group tolerance, commonly used for constructing biaryl structures.
Heck Coupling: The coupling of alkenes with organic halides, directly forming carbon-carbon double bonds.
Buchwald-Hartwig Coupling: The coupling of amines with aryl halides. It is considered the gold standard for constructing C-N bonds (e.g., in arylamines and nitrogen-containing heterocycles).
Ullmann Coupling: A traditional method for the copper-catalyzed coupling of aryl halides to form C-O and C-N bonds, with modern改良 versions featuring milder conditions.
02
/Other CDMO Projects
Coupling chemistry
The company is dedicated to the synthesis of small molecule compounds, with a particular focus on the custom synthesis of intermediates for early-stage drug development applications.
03
/Other CDMO Projects
The company is dedicated to the synthesis of small molecule compounds, with a particular focus on the custom synthesis of intermediates for early-stage drug development applications.
03
/电话
联系人：闫经理 电话：18994105658
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